CMA is an immune-mediated response to proteins in cow’s milk that can be IgE-mediated or non-IgE-mediated, depending on how the immune system reacts.1,2 Both types can present diverse clinical symptoms, which can vary in severity and speed of onset.1,2
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The iMAP guideline encourages early recognition of CMA, which should be achieved through a physical examination and taking a thorough allergy-focused clinical history.2-4
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The diagnosis of suspected CMA can only be confirmed or excluded by an allergy test or a reintroduction trial of dietary cow’s milk protein.2,4
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References
IE-SIMILAC-2100003 February 2021
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