Acts as food for bacteria, selecting only the good kinds6–9
For parents and carers of infants who have been prescribed or recommended a specialist formula by a healthcare professional.
Information about our non-specialty formulas, including Similac® First Infant Milk and Similac® Follow On Milk.
As mentioned on 'the early immune system' page, breast milk contains a number of ingredients that help babies develop their immune system.1–3
One important ingredient is a type of carbohydrate called 'human milk oligosaccharides' (pronounced 'oh-lee-go-sack-a-rides') or 'HMOs', which are one of the largest solid components of breast milk.4
The most common type of HMO that most mothers naturally produce is called ‘2’-fucosyllactose’ (pronounced ‘foo-co-sill-lack-tose’).5 For short, we just call it ‘2-FL’.
Unlike fat, protein, and many other carbohydrates, 2’-FL resist digestion until they reach the intestine,5 where they help support the immune system in a number of ways:
Acts as food for bacteria, selecting only the good kinds6–9
Blocks bad bacteria from attaching to the gut and infecting baby9
Strengthens the gut barrier to prevent bad bacteria from entering the blood6,8
Small amount is absorbed in the blood to boost the immune system around the body5,10,11
Abbott have spent over two decades researching and testing how to add this ingredient into infant formula.
However, the 2'-FL in our formulas is not made from breast milk, but is instead produced in a similar way to the way some vitamins are made.12
IMPORTANT NOTICE: Breastfeeding is best for infants and is recommended for as long as possible during infancy. Alimentum and EleCare are infant formulas for special medical purposes and should only be used under the recommendation or guidance of a healthcare professional.
*The 2'-FL (2'-fucosyllactose) used in this formula is biosynthesised and structurally identical to the human milk oligosaccharide (HMO) 2'-FL, found in most mothers' breast milk.5
UK-SIMILAC-2000018 November 2020
References
1. Oddy WH. Ann Nutr Metab. 2017;70(suppl 2):26–36.
2. Kainonen E, Rautava S, Isolauri E. Br J Nutr. 2013;109(11):1962–1970.
3. Boix-Amorós A, et al. Nutr Rev. 2019;77(8):541–556
4. Bode L. Glycobiology. 2012;22(9):1147–1162.
5. Reverri EJ, et al. Nutrients. 2018;10(10):1346
6. Akkerman R, et al. Crit Rev Food Sci Nutr. 2019;59(9):1486–1497.
7. Salli K, et al. Sci Rep. 2019;9(1):13232.
8. Ayechu-Muruzabal V, et al. Front Pediatr. 2018;6:239.
9. Hegar B, et al. Pediatr Gastroenterol Hepatol Nutr. 2019;22(4):330–340.
10. Goehring KC, et al. J Nutr. 2016;146(12):2559–2566.
11. Marriage BJ, et al. J Pediatr Gastroenterol Nutr. 2015;61(6):649–658.
12. Abbott Nutrition. Questions about 2’-FL? Available at: https://static.abbottnutrition.com/cms-prod/similac-2015.com/img/faq-similac-2017-hmo.pdf (accessed January 2021).